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The South-Central United States is a treasure trove for backpackers seeking diverse landscapes without the crowds of the West Coast. From rugged deserts to rolling forests and towering canyons, this region offers multi-day trails, affordable camping, and a mix of beginner-friendly and challenging routes. Backpackers can explore 100+ miles of trails in one park, witness dramatic elevation changes, and enjoy stargazing far from city lights. Here are six top destinations that promise unforgettable experiences and measurable adventure statistics.
1. Big Bend National Park, Texas

Big Bend stretches across 801,000 acres of desert, mountains, and river valleys, offering over 150 miles of marked backpacking trails. Hikers can tackle the challenging 12.6-mile South Rim Trail for panoramic views or explore the Rio Grande corridor for 25 miles of scenic river hiking. Backcountry permits cost $12 per night, with more than 200 campsites available. Peak backpacking season runs October through March, when daytime temperatures average 70°F and nights dip to 40°F, providing ideal conditions for solitude and star-filled skies.
2. Ouachita National Forest, Arkansas & Oklahoma

Spanning 1.8 million acres across two states, the Ouachita National Forest features more than 200 miles of interconnected trails, including the 223-mile Ouachita Trail. Backpackers can navigate forested ridges, clear streams, and rolling hills while camping at primitive sites for free. Average daily temperatures range from 60°F in spring to 75°F in fall, with minimal rainfall in October. Nearby towns like Mena and Hot Springs offer budget resupply points. Wildlife sightings include white-tailed deer, black bears, and over 150 bird species, making it ideal for nature enthusiasts.
3. Guadalupe Mountains National Park, Texas

Guadalupe Mountains rise sharply from the West Texas desert, reaching 8,751 feet at Guadalupe Peak, the state’s highest point. Trails like the 8.4-mile Guadalupe Peak Trail challenge backpackers with steep elevation gain and sweeping vistas. The park has 35 backcountry campsites, and permits cost $8 per night. Spring and fall are optimal for trekking, with highs near 70°F and lows around 40°F. Hikers can combine desert canyon routes and mountain ridges for multi-day adventures while spotting species like mountain lions, javelinas, and golden eagles along the way.
4. Ozark Highlands Trail, Arkansas

The Ozark Highlands Trail spans approximately 165 miles through dense hardwood forests, limestone bluffs, and river valleys. Backpackers can camp at 20 primitive shelters or designated dispersed sites without permits. Daily trail mileage averages 10–15 miles, with elevation gains reaching 800 feet per section. Spring sees average highs of 65°F and vibrant wildflowers, while autumn offers cooler 55°F days and vivid foliage. Water sources are abundant, with multiple springs and streams along the route. Towns like Clarksville and Jasper provide easy resupply points for extended trips.
5. Wichita Mountains Wildlife Refuge, Oklahoma

Covering 59,000 acres, the Wichita Mountains offer granite peaks, prairie trails, and desert-like landscapes perfect for backpacking excursions of 2–5 days. The Refuge Trail System includes over 15 miles of multi-use paths connecting backcountry campsites. Spring and fall feature moderate highs near 70°F and lows around 45°F. Wildlife includes bison, elk, and prairie dogs, providing memorable encounters. Permits are free, and water is available at select sites. The area is ideal for short but immersive backpacking trips, blending physical challenge with accessible adventure.
6. Palo Duro Canyon State Park, Texas

Palo Duro Canyon is the second-largest canyon in the U.S., spanning 120 miles and cutting up to 800 feet deep. Backpackers can explore over 30 miles of designated trails, camping at 10 backcountry sites with minimal fees of $5–$10 per night. Spring and fall offer comfortable highs of 70–75°F and lows of 45–50°F. The canyon features colorful geological formations, arroyos, and intermittent streams. Its proximity to towns like Amarillo allows easy resupply. The park suits both beginners seeking scenic hikes and seasoned backpackers planning overnight canyon adventures.